Medical research background
Investigation Updated: December 5, 2025

Best Online GLP-1 Program 2025

We investigated 10 telehealth providers offering Semaglutide and Tirzepatide. Here's our unbiased ranking based on pricing transparency, medication quality, and customer support.

3 Verified Safe
4 Approved
3 Under Watch
100+ Hours ResearchIndependent AnalysisRed Flags Exposed

What We Investigate

Our research methodology for provider reviews

Pricing Transparency

We verify if advertised prices include all fees, medications, and consultations.

Medication Quality

We check if providers use FDA-approved or properly compounded medications.

Customer Support

We evaluate response times, availability, and quality of medical guidance.

Understanding GLP-1 Medications

Weight management involves FDA-approved medications as part of comprehensive, medically supervised plans. Here's what you need to know.

How Weight Loss Medications Work

Weight management is not solely about appearance — it addresses significant health risks like diabetes, hypertension, and cardiovascular disease. GLP-1 medications target biological factors including appetite regulation and metabolic rate. All medications require qualified healthcare provider supervision.

Potential Benefits

Reduced Appetite

Medications target hunger-related hormones, helping you feel satisfied with smaller portions.

Metabolic Support

Treatments influence glucose metabolism and fat storage, supporting your body's natural processes.

Lifestyle Support

Medications complement dietary and physical activity efforts for comprehensive results.

Important Considerations

Common side effects may include:

Nausea
Headaches
Gastrointestinal discomfort
Injection site reactions
Dizziness

Always discuss risks and benefits with your healthcare provider before starting any medication.

Medication Options

GLP-1 Receptor Agonists

Semaglutide, Liraglutide

FDA-Approved

Wegovy® and Saxenda® regulate appetite and food intake for individuals meeting specific BMI criteria or with weight-related comorbidities, combined with lifestyle interventions.

Tirzepatide

Mounjaro®

FDA-Approved

FDA-approved for type 2 diabetes; being studied for weight loss. Off-label weight loss use requires healthcare provider discussion.

Combination Approaches

Zepbound™

FDA-Approved

Combines mechanisms targeting multiple hormonal pathways for appetite and metabolism. Requires prescription and professional monitoring.

Compounded Medications

Compounded Semaglutide & Tirzepatide

Verify Credentials

Compounded versions made by pharmacies. Not the same as FDA-approved brand names. Verify pharmacy credentials and understand the differences.

Taking the Next Steps

Consult licensed healthcare providers to determine if medication is appropriate for you, discuss benefits and risks, and create a tailored treatment plan that fits your lifestyle and health goals. Use our research to choose a reputable provider.

Frequently Asked Questions

Get answers to the most common questions about weight loss treatments.

Have more questions? Visit our full FAQ page

Important Note

  • • Medications should not be purchased online without valid prescriptions from licensed healthcare providers
  • • Efficacy claims must be based on clinical data and individual patient assessments
  • • Prioritize safety, compliance, and transparency in healthcare services