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GLP-1 Agonist Dosage Chart: Complete Guide
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Guides9 min readApril 10, 2026

GLP-1 Agonist Dosage Chart: Complete Guide

A comprehensive dosage reference for all GLP-1 medications. Starting doses, titration schedules, and maximum doses.

By Med Consumer Watch Team
Here's a comprehensive reference comparing dosing for all major GLP-1 medications used for diabetes and weight loss.

Tirzepatide (GLP-1/GIP Dual Agonist)

Mounjaro/Zepbound dosing:
  • Start: 2.5mg weekly
  • Titration: Increase 2.5mg every 4 weeks
  • Maximum: 15mg weekly
  • Full titration time: ~20 weeks

Semaglutide

Wegovy (weight loss): • Start: 0.25mg weekly • Titration: 5 steps over 16-20 weeks • Maximum: 2.4mg weekly Ozempic (diabetes): • Start: 0.25mg weekly • Maximum: 2mg weekly

Liraglutide

Saxenda (weight loss): • Start: 0.6mg daily • Titration: Increase 0.6mg weekly • Maximum: 3.0mg daily Victoza (diabetes): • Maximum: 1.8mg daily

Key Titration Principles

Common across all GLP-1s: • Start low to minimize GI side effects • Titrate gradually over weeks • Stay at current dose if side effects limiting • Not everyone needs maximum dose • Work with provider to optimize

Never rush titration. Faster dose increases lead to worse side effects and higher dropout rates.

Comparison Table

Maximum weekly doses for weight loss: • Tirzepatide (Zepbound): 15mg • Semaglutide (Wegovy): 2.4mg • Liraglutide (Saxenda): 21mg (3mg × 7 days) Effectiveness roughly follows this order, with tirzepatide producing the most weight loss.

The Bottom Line

All GLP-1 medications use gradual titration starting with low doses. Tirzepatide and semaglutide are the most effective options, with tirzepatide leading in weight loss results. Work with your healthcare provider to find the optimal medication and dose for your situation.

Sources & References

  • FDA - GLP-1 Agonist Prescribing Information

Medical Disclaimer

This article is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making decisions about your health or medications. Individual experiences may vary.

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Mounjaro Dosage Chart

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Wegovy Dosage Chart

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