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Guides8 min readMarch 14, 2025
Mounjaro Dosage Chart: From 2.5mg to 15mg
Complete Mounjaro dosing guide. Understanding the titration schedule and how to optimize your dose for best results.
By Med Consumer Watch Team
Mounjaro (tirzepatide) uses a gradual titration schedule to minimize side effects while building to an effective dose. Here's the complete dosing guide.
Mounjaro Dosing Schedule
Standard titration:
- Weeks 1-4: 2.5mg once weekly (starting dose)
- Weeks 5-8: 5mg once weekly
- Weeks 9-12: 7.5mg once weekly
- Weeks 13-16: 10mg once weekly
- Weeks 17-20: 12.5mg once weekly
- Week 21+: 15mg once weekly (maximum dose)
You can stay at any dose that's working well. Not everyone needs to reach 15mg.
Key Points
Important dosing information:
• Inject once weekly on the same day each week
• Day of week can be changed if needed (wait at least 3 days between doses)
• Never increase dose faster than recommended
• Skipped dose: Take as soon as remembered if within 4 days, otherwise skip
• Store in refrigerator before first use
Dose Adjustment
Work with your provider to find optimal dose:
• Stay at current dose if side effects are significant
• Increase may not be necessary if losing weight adequately
• Some people do well at lower doses
• Maximum is 15mg but not everyone needs it
Never increase your dose without your provider's guidance. Faster titration increases side effects.
Pen Strengths Available
Mounjaro comes in single-dose pens:
• 2.5mg/0.5mL
• 5mg/0.5mL
• 7.5mg/0.5mL
• 10mg/0.5mL
• 12.5mg/0.5mL
• 15mg/0.5mL
Each pen is used once then discarded.
The Bottom Line
Mounjaro's titration schedule takes 20+ weeks to reach maximum dose. This gradual approach minimizes side effects. Work with your provider to find the dose that balances effectiveness with tolerability for you.
Sources & References
- FDA - Mounjaro Prescribing Information
Medical Disclaimer
This article is for informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making decisions about your health or medications. Individual experiences may vary.