Compounded
Semaglutide
Any prescribed dose up to 2.5 mg/week
Prescription & clinician review included
Shipping included
$948 due today
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Investigation Report
Clinic 45 Semaglutide Review
Clinic 45, Clinic45 Houston, clinic45.com
Also spelled as Clinic 45, Clinic45 Houston, clinic45.com — Same brand, same great service!
Our investigation of Compounded Semaglutide from Clinic 45
Caution Advised
Multiple red flags identified
Caution Advised
Service packages and pricing options are published on the practice's site; specific figures were not extractable
100+
Hours Researched
6
Verified Pros
7
Issues Found
6.7
Final Score
These are Med Consumer Watch products, not products from Clinic 45, the brand being reviewed on this page.
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Compounded
Tirzepatide
Any prescribed dose up to 15 mg/week
Prescription & clinician review included
Shipping included
$1,548 due today
Treatment requires a prescription and clinician approval. If treatment is declined, your payment is refunded. Compounded medications are not FDA-approved.
Investigation Overview
Clinic 45 combines a wide Houston footprint with a diet-plus-medication model. Our research (August 8, 2026) found six locations and a structure built around ongoing contact.
Six Locations Plus Telehealth
The practice states it operates 6 locations across the Houston area, and provides "telehealth for weight loss consultations and check-ups." That combination is practically useful: in-person access for the initial evaluation and injections, with remote follow-up for routine check-ins. Six sites across a metro the size of Houston means most patients have a location within reach.Medication Sits Inside a Diet Plan
"At Clinic 45, we are passionate about promoting obesity prevention and helping to promote a healthy lifestyle for the entire family. In addition to providing our clients with a personalized low-carb diet plan, and prescription weight loss program, we also perform... telehealth for weight loss consultations and check-ups."Pairing a personalised dietary plan with the prescription is the correct structure — the trials that generated the results this industry quotes included lifestyle intervention throughout. The family and prevention framing is broader than most practices attempt, though the low-carb specificity is a choice rather than a requirement; the evidence supports adequate protein and an overall energy deficit more strongly than any particular macronutrient pattern.
Internal Medicine on the Menu
The practice offers internal medicine consultations alongside weight loss, which means GLP-1 care can sit within broader primary care rather than in isolation. That matters clinically, since GLP-1 eligibility and safety depend on comorbidities and concurrent medications.Packages and Pricing
Clinic 45 refers patients to "service packages and pricing options" on its site. We could not extract specific figures from the material we reviewed, but the existence of published package structures is a better starting point than the complete pricing silence common elsewhere — ask for the schedule directly.What Is Not Published
Whether the semaglutide is brand-name or compounded, and no named pharmacy or 503A/503B status. No BMI or eligibility criteria, no stated lab requirements, no dosing protocol, no monitoring cadence, and no clinician credentials in the material we reviewed. For a six-location practice offering internal medicine, those omissions are more surprising than they would be at a single med spa — the clinical infrastructure appears to be there, but the disclosures are not.Where It Fits
If you are in Houston and want medication paired with a real dietary plan, delivered from a location near you with telehealth follow-up, the structure fits. Bring the product and pricing questions to the first visit.Our Investigation Summary
Our research (August 8, 2026) found Clinic 45 operating six locations across the Houston area, offering semaglutide injections alongside a personalised low-carb diet plan, internal medicine consultations, and telehealth for weight loss consultations and check-ups. The combination of six physical sites with remote follow-up is practically useful across a metro of Houston's size, giving in-person access for evaluation and injections with telehealth for routine check-ins. Pairing a personalised dietary plan with the prescription is the correct structure, since the trials generating the results this industry quotes included lifestyle intervention throughout — though the low-carb specificity is a choice rather than a requirement, as the evidence supports adequate protein and an overall energy deficit more strongly than any particular macronutrient pattern. Offering internal medicine consultations alongside weight loss means GLP-1 care can sit within broader primary care rather than in isolation, which matters because eligibility and safety depend on comorbidities and concurrent medications. The practice frames its mission around obesity prevention and healthy lifestyle for the whole family, and refers patients to published service packages and pricing options, though we could not extract specific figures. Not published: whether the semaglutide dispensed is brand-name or compounded, the pharmacy and its 503A or 503B status, BMI or eligibility criteria, lab requirements, dosing protocols, monitoring cadence, or clinician credentials — omissions more surprising at a six-location practice offering internal medicine than they would be at a single med spa, since the clinical infrastructure appears present even where the disclosures are not.
How Clinic 45 Works
1
Choose from six Clinic 45 locations across the Houston area
2
Book a consultation — internal medicine consultations are available alongside weight loss
3
Review the published service packages and pricing options with the practice
4
Treatment combines semaglutide injections with a personalised low-carb diet plan
5
Telehealth is available for weight loss consultations and routine check-ups
6
Ask whether the semaglutide is brand-name or compounded and which pharmacy supplies it
What We Found
What's Good
- Six locations across the Houston area for wide in-person access
- Telehealth available for consultations and routine check-ups
- Semaglutide paired with a personalised diet plan rather than prescribed alone
- Internal medicine consultations available, so GLP-1 care can sit within broader primary care
- Publishes service packages and pricing options rather than complete pricing silence
- Framing around obesity prevention and family-wide healthy lifestyle
Watch Out For
- Specific pricing figures not extractable from the material we reviewed
- Does not state whether semaglutide is brand-name or compounded
- No named pharmacy and no 503A/503B status disclosed
- No published BMI thresholds, eligibility criteria or lab requirements
- No dosing protocol, monitoring cadence or clinician credentials published
- Low-carb specificity is a practice preference rather than an evidence requirement
- Tirzepatide does not appear prominently in the published offering
Pricing Breakdown
Starting Price
Not extracted. The practice refers patients to published service packages and pricing options
Medication Cost
Not published in the material we reviewed. Semaglutide injections are offered
Subscription Fees
Service packages are referenced rather than a subscription model
Hidden Fees
Not established. Package structures are referenced on the site; ask for the full schedule directly
Safety & Medical Oversight
Clinic 45 delivers care from six physical locations across the Houston area with telehealth available for consultations and check-ups, and offers internal medicine consultations alongside its weight loss services — meaning GLP-1 care can be managed within a broader primary care context rather than in isolation, which is clinically relevant since eligibility and safety depend on comorbidities, concurrent medications and history. Medication is paired with a personalised low-carb diet plan, reflecting the structure of the clinical trials, in which participants received lifestyle intervention alongside the drug throughout. The low-carb specificity is a practice preference rather than an evidence requirement; the more important nutritional considerations during GLP-1 treatment are adequate protein intake to protect lean mass and an overall energy deficit, and patients should ensure protein adequacy is addressed regardless of the carbohydrate approach. What we could not establish: whether the semaglutide dispensed is FDA-approved brand-name product or a compounded preparation, which pharmacy supplies it, whether that pharmacy operates under 503A or 503B, what BMI or clinical eligibility thresholds apply, whether laboratory work is required before prescribing, what dosing titration protocol is used, what monitoring schedule applies, and what credentials the treating clinicians hold. Patients should establish each at their first visit. If compounded medication is used, compounded drugs are not FDA-approved and are not reviewed for safety, effectiveness or manufacturing quality. GLP-1 receptor agonists carry a boxed warning for thyroid C-cell tumours and are contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2.
Customer Support
Clinic 45's six Houston-area locations give patients in-person access across a large metropolitan region, with telehealth available for weight loss consultations and check-ups so routine follow-up does not require travel. The practice provides a personalised low-carb diet plan as part of the program rather than as a separate purchase, and offers internal medicine consultations for patients wanting broader care from the same practice. Published service packages and pricing options give patients a structure to review, though we could not extract specific figures. We found no published support hours, response-time commitments, clinician credentials, monitoring cadence, cancellation policy or refund terms.
Key Features
Six Houston-Area Locations
Semaglutide Injections
Personalised Low-Carb Diet Plan
Telehealth Consultations and Check-Ups
Internal Medicine Available
Published Service Packages
Obesity Prevention Focus
Family-Oriented Approach
Best For
Houston patients who want medication paired with a real dietary plan from a nearby location, with telehealth for routine follow-up
Customer Reviews & Complaints
We assessed Clinic 45 against its published material as of August 8, 2026.
What we verified directly: six locations across the Houston area; semaglutide injections offered; a personalised low-carb diet plan provided alongside the prescription weight loss program; telehealth for weight loss consultations and check-ups; internal medicine consultations available; referenced service packages and pricing options; and a stated focus on obesity prevention and healthy lifestyle for the whole family.
The structure is the strength. Six sites plus telehealth follow-up plus a dietary plan plus internal medicine access is a more complete clinical package than most operators assemble, and it addresses the parts of treatment that medication alone does not.
The disclosure gap is the weakness, and it is more conspicuous here. A six-location practice offering internal medicine plainly has clinical infrastructure; not stating whether its semaglutide is brand-name or compounded, or naming the pharmacy, is a choice rather than a constraint.
What we could not establish: specific pricing, brand-name versus compounded status, the dispensing pharmacy and its regulatory pathway, eligibility criteria, lab requirements, dosing and monitoring protocols, clinician credentials, founding year, refund terms, or independent third-party review aggregates.
Is Clinic 45 Legit?
"Is Clinic 45 legitimate?" Our assessment as of August 8, 2026.
Official Verification: Clinic 45 operates six physical locations across the Houston area, offers internal medicine consultations, and provides telehealth follow-up. A multi-site practice with a primary care service line is a substantial clinical operation. We found no evidence of wrongdoing.
The model is well constructed. Medication plus a personalised dietary plan plus telehealth check-ups plus access to internal medicine covers considerably more of the treatment picture than a shipped vial. Trials paired medication with lifestyle intervention throughout, and this practice is built that way.
One nutritional note. Low-carb is a legitimate approach but not the critical variable on a GLP-1. Protein adequacy is — appetite suppression makes under-eating protein easy at exactly the point lean mass is at risk. Ask that the plan address protein specifically, whatever its carbohydrate framing.
The questions to bring are the standard three: what does it cost, is the medication brand-name or compounded, and which pharmacy supplies it. The practice publishes packages, so the first should be readily answered.
Red Flags Check:
- ✓ Six verifiable Houston-area locations
- ✓ Telehealth follow-up alongside in-person care
- ✓ Personalised diet plan included with the prescription
- ✓ Internal medicine consultations available
- ✓ Service packages and pricing referenced publicly
- ⚠ Specific pricing figures not extractable
- ⚠ Brand-name versus compounded status not stated; pharmacy not named
- ⚠ No eligibility criteria, lab requirements or monitoring cadence
- ⚠ Clinician credentials not published
- ⚠ Low-carb emphasis rather than protein emphasis
The Bottom Line: A well-structured Houston practice — medication, diet plan, telehealth follow-up and internal medicine access across six locations. Ask for the package pricing schedule, establish whether the semaglutide is brand-name or compounded, and make sure the dietary plan addresses protein and not just carbohydrates. As always, consult your personal physician before starting any new medication program.
Our Verdict: Caution Advised
Clinic 45 has a 6.7/10 site score. We've identified some concerns that potential customers should be aware of. We recommend reviewing our top picks before proceeding.
Visit Clinic 45Clinic 45
Caution Advised
6.7/10
Service packages and pricing options are published on the practice's site; specific figures were not extractable
Prescription treatment requires clinician review
Investigation Summary
Overall Rank#190 of 226
Rating6.7/10
StatusCaution Advised
PricingService packages and pricing options are published on the practice's site; specific figures were not extractable
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