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Investigation Report

Yucca Health Semaglutide Review

Yucca, tryyucca.com, Yucca Health Inc, Yucca GLP-1

Also spelled as Yucca, tryyucca.com, Yucca Health Inc, Yucca GLP-1 — Same brand, same great service!

Our investigation of Compounded Semaglutide from Yucca Health

Under Watch
Some concerns noted, proceed with caution
7.9/10
Good
Rank#105 of 107
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FDA-approved medications
Under Watch

Semaglutide+B12 $125-146/mo; tirzepatide+B12 $225-258/mo depending on plan

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100+
Hours Researched
6
Verified Pros
6
Issues Found
7.9
Final Score

Investigation Overview

Yucca Health consultation process
Yucca Health—found at tryyucca.com and operated by Yucca Health, Inc.—is one of the better-documented newer GLP-1 telehealth services. Our research (checked July 25, 2026) verified named physicians, published clinical eligibility criteria, real review volume, and plan pricing—along with refund mechanics worth understanding before prepaying.

Medications and Verified Pricing

From Yucca's pages as of July 2026 (both GLP-1 formulations include a B12 boost):
  • Compounded semaglutide+B12—$146/month "for life" with code YUCCA4LIFE, or a six-month plan at $750 total ($125/month effective)
  • Compounded tirzepatide+B12—$258/month, or six months at $1,350 ($225/month effective)
  • NAD+ and sermorelin—from $158 (3-month supplies); peptides listed as coming soon
Plans include licensed providers in all 50 states, provider review within 24 hours, a patient portal, and free expedited 2-day UPS shipping. Affirm financing is available.

Rare Clinical Transparency

Two things most competitors don't publish: Yucca names its physicians—Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO, both board-certified in internal medicine (University of South Florida)—and it publishes its eligibility criteria: BMI 30+, or 27+ with a weight-related condition, with BMI 25+ considered case-by-case. Publishing real clinical gates is a genuinely good sign in a category where some services take anyone with a card. LegitScript and HIPAA badges are displayed, and its own FDA disclaimer is direct: compounded medications are not FDA-approved and don't undergo FDA review for safety, effectiveness, or manufacturing quality.

The Real Review Record—and the Refund Mechanics

Yucca's Trustpilot profile holds roughly 1,000 reviews at about 4.6 stars—a genuine, substantial record with consistent praise for customer service and results (its on-site badges cite 4.7 Trustpilot and 4.8 Google, close to the live numbers, which is more honest than most). The documented complaints are specific and worth knowing: one customer whom Yucca agreed deserved a partial refund reported being pushed toward store credit instead of a real refund, and another described Affirm-financing confusion where the lender claimed a balance after payoff. No refund or cancellation terms are published on the main pages, and the pharmacies are unnamed. Before prepaying a six-month plan—or financing one through Affirm—get the refund terms in writing and understand what happens to unused months.

Critical 2026 Regulatory Context

In 2026 the FDA proposed excluding semaglutide and tirzepatide from the 503B bulks list, restricting mass GLP-1 compounding. Confirm current availability and sourcing before enrolling.

Important: Compounded Medications

Yucca states it plainly: its compounded medications are prepared by licensed U.S. pharmacies, are not FDA-approved, and do not undergo FDA review. Self-reported platform figures (20,000+ active patients, 100,000+ prescriptions) are company marketing. Consult your own physician before starting.

Our Investigation Summary

Our research (July 25, 2026) found Yucca Health among the better-documented newer GLP-1 services: compounded semaglutide+B12 at $146/month price-locked (or $125/month effective on a $750 six-month plan) and tirzepatide+B12 at $258/month ($225 effective on six months), with named board-certified physicians (Dr. Michael Wasef, MD; Dr. Andrew Sakla, DO), published BMI eligibility criteria, LegitScript and HIPAA badges, 24-hour provider review, free 2-day UPS shipping, and a genuine ~4.6-star, ~1,000-review Trustpilot record whose on-site framing roughly matches reality. Key considerations: refund and cancellation terms are unpublished—with a documented store-credit-instead-of-refund case and an Affirm billing-confusion report—pharmacies are unnamed, and no address or phone is published. Best for buyers who meet the published criteria, get refund terms in writing before prepaying six months, and keep financing records.

How Yucca Health Works

1

Complete the online intake—Yucca publishes its eligibility gates (BMI 30+, or 27+ with a weight-related condition; 25+ case-by-case)

2

A provider reviews within 24 hours; care is led by named board-certified physicians (Dr. Michael Wasef, MD; Dr. Andrew Sakla, DO)

3

Choose monthly ($146 semaglutide with code YUCCA4LIFE / $258 tirzepatide) or six-month plans ($750 / $1,350)

4

Prescriptions are filled by licensed U.S. pharmacies and shipped free via 2-day UPS Air

5

Manage treatment through the patient portal with provider support

6

Before prepaying or financing via Affirm: get the refund and cancellation terms in writing—they aren't published, and refund-mechanics complaints exist

What We Found

What's Good

  • Named board-certified physicians (Dr. Michael Wasef, MD; Dr. Andrew Sakla, DO)
  • Published BMI eligibility criteria—rare clinical gating
  • Price-locked semaglutide at $146/month; six-month plans cut effective rates to $125/$225
  • Genuine ~4.6-star Trustpilot record across ~1,000 reviews; on-site badges roughly match reality
  • Provider review within 24 hours; free 2-day UPS shipping; all 50 states
  • LegitScript and HIPAA badges; direct FDA disclaimer

Watch Out For

  • Refund and cancellation terms not published
  • Documented store-credit-instead-of-refund case and Affirm billing-confusion report
  • Pharmacies unnamed; no address, phone, or email published
  • Six-month prepay ($750/$1,350) concentrates risk if treatment doesn't suit you
  • Self-reported patient/prescription counts are marketing figures
  • Compounded medications are not FDA-approved finished products; 2026 FDA compounding restrictions apply

Pricing Breakdown

Starting Price
Semaglutide+B12 $146/month price-locked (code YUCCA4LIFE) or $125/month effective on the $750 six-month plan
Medication Cost
Tirzepatide+B12 $258/month or $225/month effective on the $1,350 six-month plan; NAD+ and sermorelin from $158 (3-month supplies)
Subscription Fees
Provider review, patient portal, and free 2-day UPS shipping included; Affirm financing available
Hidden Fees
Refund/cancellation terms unpublished—documented store-credit-instead-of-refund and Affirm-confusion cases; get terms in writing before prepaying

Safety & Medical Oversight

Yucca Health medication safety
Yucca publishes real clinical gates—BMI 30+, or 27+ with a weight-related condition, 25+ case-by-case—and names its board-certified internal-medicine physicians, both checkable. Its compounded semaglutide and tirzepatide (with B12) are prepared by licensed U.S. pharmacies but are not FDA-approved and don't undergo FDA review, as its own disclaimer states; the pharmacies are unnamed, so ask which fills your prescription. GLP-1s are contraindicated with a personal or family history of medullary thyroid carcinoma or MEN 2. NAD+ and sermorelin carry limited clinical evidence for marketed benefits.

Customer Support

Patient portal with provider support; no phone number, email, or address published on the main pages—use the portal and keep communications in writing. Service praise is consistent in reviews; refund mechanics are the documented friction point, so escalate billing issues promptly and dispute through your card issuer or Affirm if needed.

Key Features

Compounded Semaglutide+B12 ($146/mo Locked)
Compounded Tirzepatide+B12 ($258/mo)
Six-Month Plans ($125/$225 Effective)
Named Board-Certified Physicians
Published BMI Eligibility Criteria
24-Hour Provider Review
Free 2-Day UPS Shipping
NAD+ & Sermorelin (From $158)

Best For

Buyers who meet the published eligibility criteria and want named-physician care at locked pricing—who get refund terms in writing before prepaying six months

Customer Reviews & Complaints

Our team reviewed available customer feedback for Yucca Health (tryyucca.com) as of July 2026.

Trustpilot: Roughly 1,000 reviews at about 4.6 stars—a genuine, substantial record for a 2025-launched service, with consistent praise for customer service and treatment results. Notably, Yucca's on-site badges (4.7 Trustpilot, 4.8 Google) roughly match the live numbers—more honest framing than most competitors.

Documented Complaints: Two specific cases stand out: a customer whom Yucca agreed deserved a partial refund reported being pushed toward store credit rather than an actual refund, and another described Affirm claiming an outstanding balance after the customer had completed payments. Both point to refund-and-financing mechanics as the friction zone.

Overall Complaint Analysis: The pattern is narrow but instructive: the clinical product satisfies most reviewers, while money-back situations are where diligence pays. Practical defenses: get refund and cancellation terms in writing before prepaying a six-month plan, keep Affirm statements and payoff confirmations, insist on refunds to your original payment method, and dispute promptly if offered store credit for an agreed refund.

Is Yucca Health Legit?

A common question about newer providers is: "Is Yucca Health legit?" Here's our assessment as of July 2026.

Official Verification: Yucca Health, Inc. is a real telehealth operation with named, board-certified physicians (Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO—both verifiable), published clinical eligibility criteria, LegitScript and HIPAA badges, and a genuine four-figure review base at strong ratings.

Licensing & Accreditation: Prescriptions are filled by licensed U.S. pharmacies—unnamed, so ask which serves you—and its FDA disclaimer is direct: compounded medications are not FDA-approved and don't undergo FDA review.

Red Flags Check: We looked for common warning signs:

  • ✓ Named board-certified physicians
  • ✓ Published BMI eligibility gates—real clinical screening
  • ✓ Substantial genuine review record whose on-site framing matches reality
  • ✓ Price-locked and published plan pricing; LegitScript badge
  • ⚠ Refund/cancellation terms unpublished; store-credit and Affirm complaint cases
  • ⚠ Pharmacies unnamed; no published address, phone, or email
  • ⚠ Six-month prepays concentrate refund risk

Scam Assessment: Yucca is not a scam—it's one of the more clinically transparent newcomers, with a real satisfied customer base. The caution is financial mechanics: know the refund terms before your money is committed.

The Bottom Line: Named doctors, real eligibility gates, honest badges, and competitive locked pricing make Yucca a strong newcomer—just settle the refund terms in writing before prepaying, and keep financing records. As always, consult your personal physician before starting any new medication program.

Our Verdict: Under Watch

After our comprehensive investigation, Yucca Health receives a 7.9/10 rating. While this provider meets basic standards, there are some areas for improvement. Consider comparing with our top-rated options before making a decision.

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Yucca Health

Under Watch
7.9/10

Semaglutide+B12 $125-146/mo; tirzepatide+B12 $225-258/mo depending on plan

Visit Yucca Health
FDA-approved medications

Investigation Summary

Overall Rank#105 of 107
Rating7.9/10
StatusUnder Watch
PricingSemaglutide+B12 $125-146/mo; tirzepatide+B12 $225-258/mo depending on plan

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